Memory T cell - Wikipedia
Central memory T cells (T CM cells) express CD45RO, C-C chemokine receptor type 7 (CCR7), and L-selectin (CD62L). Central memory T cells also have intermediate to high expression of CD44. This memory subpopulation is commonly found in …
中央记忆型T细胞 - 百度百科
中央记忆型T细胞（Central Memory T cell）的简称，是幼稚T细胞（Naive T Cell）经过抗原激活后，产生的具有长期记忆性的，并能够归巢到淋巴结接受抗原再刺激的T细胞。
Central memory and effector memory T cell subsets: function ... - PubMed
Recent studies indicate that memory T lymphocytes contain distinct populations of central memory (TCM) and effector memory (TEM) cells characterized by distinct homing capacity and effector function. This review addresses the heterogeneity of TCM and TEM, their differentiation stages, and the current models for their generation and maintenance ...
CD4+ T cell memory | Nature Immunology
May 8, 2023 · Memory CD4 + T cells are positioned throughout the body and not only protect the tissues from reinfection and cancer, but also participate in allergy, autoimmunity, graft rejection...
Two parallel worlds of memory T cells - Nature Immunology
Oct 28, 2020 · In this issue of Nature Immunology, Galletti et al. 3 discover a population of cells within the memory compartment that shows memory features and key elements of exhausted T cell...
Central Memory and Effector Memory T Cell Subsets: Function, …
Recent studies indicate that memory T lymphocytes contain distinct populations of central memory (TCM) and effector memory (TEM) cells characterized by distinct homing capacity and effector function. This review addresses the heterogeneity of TCM and TEM, their differentiation stages, and the current models for their generation and maintenance ...
A primary role for human central memory cells in tissue ...
Feb 6, 2018 · Central memory T cells (T CM) coexpress L-selectin and CCR7 and provide central immunosurveillance by patrolling the lymph nodes draining peripheral tissue sites. 1,2 In mice and nonhuman primates, T CM provide effective long-term protection because they persist long term in the circulation, have a high proliferative potential, and can give ...
Central memory T cells are the most effective precursors of …
Apr 22, 2022 · We report here our findings that CCR7 + L-selectin + central memory T cells (T CM) are the most efficient precursors for human skin T RM. We tested three major circulating CD45RA − memory T cell subsets for their ability to generate T RM (Fig. 1A).
Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells …
Nov 17, 2020 · Central memory CD8 + T cells (Tcm) control systemic secondary infections and can protect from chronic infection and cancer as a result of their stem-cell-like capacity to expand, differentiate, and self-renew. Central memory is generally thought to emerge following pathogen clearance and to form based on the de-differentiation of cytolytic ...
Central memory T cells are the most effective precursors of
Apr 22, 2022 · In summary, T CM are highly efficient precursors of human skin T RM, a feature that may underlie their known association with effective long-term immunity. The circulating precursor cells that give rise to human resident memory T cells (T<sub>RM</sub>) are …