Adenovirus genome - Wikipedia
Adenovirus genomes are linear, non-segmented double-stranded (ds) DNA molecules that are typically 26-46 Kbp long, containing 23-46 protein-coding genes. [1] The example used for the following description is Human adenovirus E, a mastadenovirus with a 36 Kbp genome containing 38 protein-coding genes. [ 2 ]
Adenovirus Genome - an overview | ScienceDirect Topics
An Adenovirus Genome refers to a linear double-stranded DNA molecule of approximately 26-45 kb in length that contains genes encoding the major proteins required for viral DNA replication and major structural components.
Addgene: Adenovirus Guide
The adenovirus genome is a linear, 36-Kb double-stranded DNA (dsDNA) molecule containing multiple, heavily spliced transcripts. At either end of the genome are inverted terminal repeats (ITRs). Genes are divided into early (E1-4) and late (L1-5) transcripts. There are 57 accepted human adenovirus types, and most adenoviral vectors are based on Ad5.
Adenoviruses - Medical Microbiology - NCBI Bookshelf
Most of the adenovirus-induced tumors, tumor cell lines, and transformed cell lines carry one or several copies of the viral genome integrated into the chromosomes. The tumor or transformed state is also associated with the differential expression of the integrated viral genes.
Adenovirus Structure: What Is New? - PMC - PubMed Central (PMC)
Inside the capsid, a large amount of virus encoded, DNA-binding proteins accompany the adenovirus genome, forming a non-icosahedral core. Some of them (the core proteins) are considered DNA-condensing agents due to their positive charge [38,39].
Adenovirus Genome - an overview | ScienceDirect Topics
1999年9月13日 · The adenovirus genome is a single linear molecule of double-stranded DNA (26 163–48 395 bp) containing an inverted terminal repeat (ITR) of 30–371 bp at its termini, with the 5′ ends of each DNA strand linked covalently to a virus-coded terminal protein (TP).
Adenovirus DNA Replication - PMC
In recent years, new DNA amplification techniques and sequencing efforts have led to the identification of many new human and nonhuman adenoviruses (AdV). The human adenoviruses (HAdV) are grouped as seven species (formerly called “subgroups”), HAdV-A–G, in the Mastadenovirus genus.