The crucial role of l-arginine in macrophage activation: What you need ...
2015年9月15日 · Because the effects of l-arginine are crucial for understanding its role during nutritional and pharmacological interventions, this mini review focuses on the characterization …
Functions of Arginase Isoforms in Macrophage Inflammatory Responses ...
2021年10月27日 · In this article, we will review recent developments on the functional roles of the two arginase isoforms in regulation of macrophage inflammatory responses by focusing on …
Arginine and macrophage activation - PubMed
Therefore, the study of the arginine transport for amino acid system transporters may be a key regulatory step for physiological responses in macrophages. In this chapter, we present simple …
“Of Mice and Men”: Arginine Metabolism in Macrophages - PMC
Macrophages from some mouse strains (e.g., the M1-biased C57BL/6 strain) can be stimulated by lipopolysaccharide (LPS) to produce considerable quantities of NO. Macrophages from others …
The roles of arginases and arginine in immunity - Nature
2024年10月17日 · ARG1 regulates immune functions in myeloid-derived suppressor cells (MDSCs), activated neutrophils, tumour-associated macrophages (TAMs) and CD4 + T cells. …
Regulation of macrophage functions by L-arginine - PMC
The marked effects of L-arginine availability on macrophage functions, together with the knowledge that these cells modify the extracellular arginine concentration in sites of …
Macrophage Metabolism of Apoptotic Cell-Derived Arginine …
2020年3月3日 · We found that continual efferocytosis is enhanced by the metabolism of AC-derived arginine and ornithine to putrescine by macrophage arginase 1 (Arg1) and ornithine …
The crucial role of l-arginine in macrophage activation: What
2015年9月15日 · Recently, some new and important facts have been published considering the role of l-arginine in the regulation of inflammatory processes in several human and mouse …
The crucial role of l-arginine in macrophage activation: What you …
2015年9月15日 · According to the recent literature, it can be concluded that l -arginine availability plays a key role in the initiation of intracellular signaling pathways that trigger the inflammatory …
Macrophage Metabolism of Apoptotic Cell-Derived Arginine …
2020年1月30日 · In inflammatory macrophages, arginine is catalyzed by inducible nitric oxide synthase (iNOS) to generate nitric oxide (NO), while in pro-resolving mouse macrophages, …