Theca cells are a group of endocrine cells in the ovary made up of connective tissue surrounding the follicle. They have many diverse functions, including promoting folliculogenesis and recruitment of a single follicle during ovulation. [2] . Theca cells and granulosa cells together form the stroma of the ovary.

内层 基质细胞 分化为多边形或梭形的膜细胞（theca cell），毛细血管丰富；外层含纤维成分较多，并有少量平滑肌。 在脑垂体分泌的 卵泡刺激素 （FSH）和 黄体生成素 （LH）的调节下，颗粒细胞和膜细胞协同作用，合成和分泌雌激素。

The theca cells are one of the endocrine cell groups located in the ovary. The theca cells comprise connective tissue surrounding the follicle and have many diverse functions and roles in the ovary; the cells are involved in folliculogenesis by secreting androgen and providing structural support for the follicle's growth [37]. Theca cells are ...

Theca cells are derived from two embryonic gonadal sources and differentiate into steroidogenic cells or fibroblast/perivascular cells, respectively, in response to oocyte and granulosa cell factors. Theca is a Latin word for a casing, outer covering, or sheath.

Theca cells function in a diverse range of necessary roles during folliculogenesis; to synthesize androgens, provide crosstalk with granulosa cells and oocytes during development, and provide structural support of the growing follicle as it progresses through the developmental stages to produce a ma …

Mammalian follicles are composed of oocytes, granulosa cells, and theca cells. Theca cells form in the secondary follicles, maintaining follicular structural integrity and secreting steroid hormones. Two main sources of theca cells exist: Wilms tumor 1 positive (Wt1 +) cells native to the ovary and Gli1 + mesenchymal cells migrated from the ...

Theca cells function in a diverse range of necessary roles during folliculogenesis; to synthesize androgens, provide crosstalk with granulosa cells and oocytes during development, and provide structural support of the growing follicle as it progresses through the developmental stages to produce a mature and fertilizable oocyte.

2023年1月4日 · Theca cells serve multiple essential functions during the growth and maturation of ovarian follicles, providing structural, metabolic, and steroidogenic support. While the function of theca...

2023年3月15日 · In the adult ovary, theca cells perform a range of roles during folliculogenesis, enabling crosstalk with granulosa cells and the oocyte. They provide all androgens required for the development of the follicle and secretion of estrogens by granulosa cells. In atretic follicles, theca cells are usually the last cell population to go through ...

2005年7月1日 · Theca cells are the endocrine cells associated with ovarian follicles that play an essential role in fertility by producing the androgen substrate required for ovarian estrogen biosynthesis. Theca cells differentiate from the interfollicular stroma in response to proteins secreted from growing follicles.