InterPro - EMBL-EBI
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
What are protein domains? | Protein classification - EMBL-EBI
Domains are distinct functional and/or structural units in a protein. Usually they are responsible for a particular function or interaction, contributing to the overall role of a protein. Domains may exist in a variety of biological contexts, where similar domains can be …
SCOP| Structural Classification of Proteins - EMBL-EBI
Latest update on 2022-06-29 includes 72,544 non-redundant domains representing 861,631 protein structures. Folds, superfamilies and families statistics here.
AlphaFold Protein Structure Database
Try searching by protein or gene name rather than specific UniProt accession. If running a sequence search, the input query should contain at least 20 amino acids, and only standard amino acids are accepted.
Searching InterPro with a batch of amino acid sequences
Sequence search results: exploring other proteins in the family; page Text search
Protein domains and features | Ensembl
The domains of the protein product of the transcript can be viewed graphically (Figure 18) or in a table (Figure 19). The domains were determined by running InterProScan on the sequences, which uses multiple protein domain prediction algorithms.
EMBL-EBI
EMBL-EBI
What are protein signatures? | Protein classification - EMBL-EBI
What are protein signatures? In order to classify proteins into families and to predict the presence of important domains or sequence features, we require computational tools. One set of such tools are the predictive models known as protein signatures .
What are sequence features? | Protein classification - EMBL-EBI
Sequence features differ from domains in that they are usually quite small (often only a few amino acids long), whereas domains represent entire structural or functional units of the protein (Figure 8).
phmmer search | HMMER - EMBL-EBI
Click the example link to add a sequence to the search box. The form requires a single sequence protein in FASTA format, with or without a header line. To search multiple sequences, (up to 500) click 'Upload a file'.