▎药明康德内容团队编辑（来源：北京大学）神经传递是大脑信息交流的基础，其过程主要依赖于两种类型的囊泡：含有神经肽的大致密核心囊泡（Large dense core vesicle，LDCV）和含有小分子神经递质的突触小囊泡（Synaptic ...

在一项新的研究中，德国马克斯-德布吕克分子医学中心原位结构生物学实验室组长Misha Kudryashev教授及其同事们揭示了突触小泡（synaptic vesicle ...

Synaptic vesicle docking and fusion are mediated by the assembly of a stable SNARE core complex of proteins, which include the synaptic vesicle membrane protein VAMP/synaptobrevin and the ...

Using cryo-electron tomography, the team was able to visualize synaptic vesicles (SVs) in 3D and confirm a potentially important protein-protein interaction. They also broadened our understanding ...

This Research Topic is part of the Synaptic Vesicle Cycle: Cellular and Molecular Mechanisms series: Synaptic Vesicle Cycle: Cellular and Molecular Mechanisms For synaptic transmission, synaptic ...

近期， 中国科学院 生物与化学交叉研究中心刘聪课题组和美国辛辛那提大学医学院刁佳杰课题组在 eLife 上合作发表了一篇题为 “N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine” 的研究论文 ...

16 This is the first report of a family with a defect in a synaptic vesicle associated protein. Further studies are needed to address whether synapsin abnormalities play a role in other patients with ...

The functioning of human cells resembles the way a city relies on a precise transport system to deliver various things and ...

Eric’s research focused on the dynamic of cell membrane s, and, in particular, on he intracellular systems – the lysosomes, Golgi apparatus endoplasmic reticulum , peroxisomes, and synaptic vesicles – ...