They found that the duplication of the gene PMP22 causes problems in the cell membrane of Schwann cells that provide the insulating cover for nerves. The team has published the results of their ...

In animal models of spontaneous inflammatory neuropathy, T cell responses to defined myelin antigens are responsible. In other human inflammatory neuropathies, there is evidence of antibody responses ...

Myelin – produced by Schwann cells in the periphery and oligodendrocytes in the CNS – is defective in diseases such as multiple sclerosis, and many myelin repair strategies aim to mitigate ...

The Pancreatic Star Alliance would particularly like to encourage young researchers to enter this exciting area of pancreatology. PSC origin (lineage tracing studies). Functions in health.

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

If the cochlear nerve is affected, a patient may experience sudden hearing loss and vertigo. A slow-growing tumor of the Schwann cells that insulates the vestibulocochlear nerve may result in ...

The Human Microglia Atlas includes 91,716 brain immune cells covering six neurologic pathologies. It characterizes the signatures of nine populations and describes the expansion of GPNMB-high ...

Thus, these models may not accurately reflect the altered genome or fluctuating levels of PMP22 in Schwann cells. This encouraged researchers to investigate the upstream pathomechanism leading to the ...

I would have been bored, except the pain was so tiring that I could barely function. I spent the days shuffling around the ...

The postulated mechanisms of injury include direct needle trauma, secondary constriction by scar, and direct nerve fiber damage, due to both axon and Schwann cell, with a breakdown in the blood ...

.Semaglutide: Novo Nordisk Semaglutide is a long-acting oral GLP-1 analogue being developed and investigated by Novo Nordisk. The drug is currently being evaluated under Phase III clinical trial for ...