The Kowalinski group at EMBL Grenoble discovered notable differences between the nuclear cap-binding complex in trypanosomes and humans, a critical component in cellular RNA metabolism. Trypanosomes ...
Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs, and an intricate frameshift site structure that regulate viral protein synthesis. These findings highlight ...
By targeting key processes like RNA splicing and modification ... Leslie's powerful and robust model systems to nail down this novel mechanism." The UC Irvine scientists partnered with Clotilde ...
"By targeting key processes like RNA splicing and modification ... Leslie's powerful and robust model systems to nail down this novel mechanism," said co-corresponding author Robert Spitale ...
For the multifaceted and complex diseases, multi-omics could define groups of patients with distinct endotypes exhibiting heterogeneous treatment responses due to their particular underlying molecular ...
Activating agents enable the efficient preparation of organozinc complexes from zinc metal and organohalides, but their mechanisms had been obscured by the heterogeneous nature of these systems.