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腾讯网
2 天
直接RNA测序解锁m6A,中国科学家揭示细胞命运调控新机制
【导读】外转录组修饰,尤其是N6-甲基腺苷(m6A),是基因表达的关键调控因子,影响着RNA的稳定性、剪接和翻译等过程。从Nanopore直接RNA测序(DRS)数据中检测m6A的传统计算方法受限于对实验验证标签的依赖,往往会导致对修饰位点的低估。在 ...
Labroots
4 天
A New Kind of Epigenetic Gene Control is Revealed
The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function... | Cell And Molecular Biology ...
腾讯网
5 天
抑制肿瘤进展和转移!中山大学陈永明团队:有前景的胃癌预后生物 ...
【导读】N6-甲基腺苷(m6A)修饰在真核细胞中是一种重要的表观遗传调节因子,在肿瘤发生和癌症进展中发挥着重要作用。然而,m6A 调控在胃癌(GC)中的详细生物学功能和潜在机制尚不清楚。1月15日,中山大学陈永明研究团队在期刊《Molecular ...
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