Translation of human pluripotent stem cells into cell therapies will require the development of standardized tests for product consistency, stability, tumorigenicity, toxicity and immunogenicity.

Ma et al. show that heterogeneous nuclear ribonucleoprotein U promotes the primed state in human pluripotent stem cells by interacting with nuclear matrix protein, Matrin-3, and regulating primed ...

A fully-automated bioreactor to culture human-induced pluripotent stem cells (hiPSCs) long-term has been developed by ...

Newly generated human embryonic stem cell‐derived atrial‐like cardiomyocytes resemble human atrial cardiomyocytes and prove to be a valuable model for pre‐clinical drug screenings to identify ...

Personalized Medicine : By combining iPSCs with genome-editing technologies like CRISPR, scientists can introduce precise genetic modifications, such as knock-outs, knock-ins, or single base changes, ...

15, to mass produce human pluripotent stem cells by placing single cells in a special liquid and allowing the cells to multiply. “I thought someone must have done it, at least with other kinds of ...

ChatGPT publisher, OpenAI, has teamed up with a longevity start-up to develop an artificial intelligence model dedicated to ...

Human induced pluripotent stem cells (hiPSCs) are considered a promising tool in medicine, with the potential to unlock treatments for many health conditions such as neurodegenerative diseases and ...

Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...

The emergence of induced pluripotent stem cell (iPSC) technology has had a great impact on the ... The resulting iPSCs carry the developmental potential of human embryonic stem cells (hESC) without ...

VALID, a Techbio startup dedicated to reshaping drug discovery with complex human induced pluripotent stem cell (iPSC) co-culture models that deliver increased predictive validity, has partnered with ...

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.