In vertebrate motor circuits, hodological patterning has been demonstrated at different ... How this pattern is established remains unclear. It is likely, given the role of Hox genes in patterning ...

This opened the door to the understanding of TH action on vertebrate development. However given the relative ease by which cretinism could be treated simply by eating animal thyroid gland or iodine ...

New studies indicate that it acts as an accessory factor for the transcriptional output of the Hox transcription factor network. Figure 1: The role of FoxP1 in motor neuron specification and ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

Cystic fibrosis is caused by mutations in the gene that produces the cystic fibrosis transmembrane conductance regulator (CFTR) protein. In people with CF, mutations in the CFTR gene can disrupt the ...

They are among the most primitive living vertebrates, so studying their genes can help researchers better understand early vertebrate evolution. "Lampreys may hold the key to understanding where ...

This study presents important analyses of the impacts of microexon deletions and loss-of-function in microexon regulators on zebrafish neurite outgrowth and gene expression, as well as adult and ...

Dec 30 (Reuters) - Sangamo Therapeutics (SGMO.O), opens new tab said on Monday that partner Pfizer (PFE.N), opens new tab has terminated their hemophilia A gene therapy co-development agreement ...

Jan. 17, 2025 — Scientists explored the evolutionary success of leaf beetles, the most diverse herbivores on Earth. They showed that symbioses with bacteria have evolved repeatedly and ...

One of the study’s most exciting discoveries involved the signaling pathways responsible for limb development. By introducing lungfish genes into mouse embryos, researchers identified changes in the ...