To address this issue, multiplexing platforms have been developed for specificity testing that contain either HLA class I and class II proteins from platelets, or antigens from transformed cell ...

Maite Rodriguez and her husband gave their 6-year-old daughter with sickle cell disease a lifeline when they conceived a ...

The most common antigen involved is human platelet antigen (HPA)-1a, responsible for 85% of FNAIT cases in Caucasians ... the highest percentage of women with genetic markers associated with increased ...

Several genetic factors have been identified. There is a well-known association between the HLA (human leukocyte antigen) region of MHC recognized as HLA-C, and specifically HLA-Cw6, and ...

Early association studies in psoriasis focused attention on HLA-Cw6 in addition to HLA-B13, HLA-B17, and the class II antigen HLA-DR7. In PsA the main additional associations have been found to be ...

Most cases are attributed to maternal antibodies against human platelet antigen-1a (HPA-1a), but anti-HPA-5b antibodies have also been identified as a potential factor. A study found that while ...

6 Importance of Human Leukocyte Antigen Analysis in mUM Human leukocyte antigen (HLA) analysis can provide both prognostic information and can be used to guide patient selection for the targeted ...

Further investigation on this immunotherapeutical approach is necessary to define the best antigen format ... Pan-HLA-DR epitope; PD: Progressive disease; plt: Platelet; Pos.: ...

Developing T-cell or vaccine therapies for pancreatic ductal adenocarcinoma (PDAC) has been challenging because of a lack of knowledge regarding immunodominant, cancer-specific antigens as PDAC are ...

platelets or plasma based on each patient’s needs. Blood types relate to the presence or absence of certain antigens that are substances that can trigger an immune response if they are foreign ...

Phenotypically, they express CD56, an isoform of the neural cell adhesion molecule, on their surface simultaneously lacking the CD3 antigen. They can be further divided into a CD56 ... specific ...