Non-invasive lineage tracing in humans relies on rare ... into the contribution of mechanical forces produced by epithelial stem cell activity in building surrounding tissues, and the roles ...

During development, stem and progenitor cells gradually commit ... to differentiation along another lineage. At several stages during normal development, epithelial cells acquire the phenotypic ...

Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood.

Lineage Cell Therapeutics, Inc. , a clinical-stage biotechnology company developing allogeneic cell therapies for unmet medical needs, today announced the closing of the second tranche of its ...

Lineage’s neuroscience focused pipeline currently includes: (i) OpRegen, a retinal pigment epithelial cell therapy in Phase 2a development under a worldwide ... a novel hypoimmune induced pluripotent ...

Here we bio-printed mesenchymal stem cells (MSCs) using a commonly used bioink sodium alginate-gelatin blends, and investigated the induction effect of MSC differentiation towards lens epithelial stem ...

capable of differentiating in vivo and in vitro along the hepatocytic or bile duct epithelial cell (BDEC) lineage. These studies provided the basis for the commonly held view that by ED15 to ED16 ...

ocularsurface.com Background/aim: Amniotic membrane (AM) transplantation effectively expands the remaining limbal epithelial stem cells in patients with partial limbal stem cell deficiency. The ...

Hypoxia-driven gene and protein changes enhance epithelial-to-mesenchymal transition, remodel the extracellular matrix, drive drug resistance, support cancer stem cells and aid evasion from immune ...

The Oregon Stem Cell Center conducts basic and applied research in the field of Stem Cell Biology with the long term goal to harness the properties of stem cells for regenerative medicine and cell ...

After years of controversy, stem cells are on the cusp of cures for conditions like epilepsy and type 1 diabetes. California Institute for Regenerative Medicine, Neurona Therapeutics, Vertex ...