Pluripotent stem cells are cells that have the capacity to self-renew by dividing and to develop into the three primary germ cell layers of the early embryo and therefore into all cells of the ...

Translation of human pluripotent stem cells ... differentiated cells is also essential. If the therapeutic effect results from secretion of factors in a regulated manner, this regulation must ...

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

The emergence of induced pluripotent stem cell (iPSC) technology has had a great impact on the field of medicine ever since the ground-breaking discovery in 2006 that overexpression of four specific ...

We identified 26 stem cell gene sets from the Stem Checker database and classified BRCA samples into stemness subtypes using consensus clustering. Prognosis, tumor microenvironment (TME) elements, and ...

Hence, this study identifies a NIC-triggered pathway regulating the stemness and tumorigenicity of ... cascades prospectively associated with the regulation of the effects of NIC on ISCs. This study ...

In their manuscript, authors Isotani et al used in vivo and ex vivo models to show that nicotine could promote stemness and tumorigenicity in murine model. The authors further provided data supporting ...

However, little research has been done on their use in MS. Induced pluripotent stem cells are adult stem cells, usually from skin cells, reprogrammed to become stem cells. There isn’t much ...

After years of controversy, stem cells are on the cusp of cures for conditions like epilepsy and type 1 diabetes. California Institute for Regenerative Medicine, Neurona Therapeutics, Vertex ...

Immune complex shaves stem cells to protect against cancer Date: January 17, 2025 Source: Weill Cornell Medicine Summary: A group of immune proteins called the inflammasome can help prevent blood ...

The Oregon Stem Cell Center conducts basic and applied research in the field of Stem Cell Biology with the long term goal to harness the properties of stem cells for regenerative medicine and cell ...

By understanding fundamental processes such as cancer development and metastasis, tissue differentiation from stem cells, and neural activation through SRF, we hope this discovery will lead to the ...