The Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Application for SL1009 (sodium dichloroacetate oral solution) for the treatment of pyruvate dehydrogenase complex ...

This important study reveals a role for IκBα in the regulation of embryonic stem cell pluripotency. The solid data in mouse embryonic stem cells include separation of function mutations in IκBα to ...

If you’re looking for low sodium meals, it can be even harder to plan and make healthy meals for the entire week. A low sodium diet plan typically involves limiting processed foods and eating ...

You must have heard about the negative effects of eating salty foods, but did you know not all high sodium foods are bad for you? While table salt is high in sodium, it is usually not the cause of ...

San Diego, CA, United States) were maintained in growth medium (GM) that was prepared by supplementing Dulbecco’s Modified Eagle Medium (DMEM, D6171, Sigma) with 10% FBS (10270-106, Gibco, Grand ...

All complete growth medias contained 10% fetal bovine serum, 1% penicillin-streptomycin, 1% nonessential amino acids, 1% L-glutamine, 1% hepes buffer, and 1% sodium pyruvate. Cells in culture had ...

pyruvate carboxylase deficiency; PA, propionic acidemia; THAN, transient hyperammonemia of the newborn; VLCADD, very long chain acyl-CoA dehydrogenase deficiency. Adapted with permission from ...