They seek to understand how cells modulate gene expression by modulating chromatin and DNA organization. Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin ...

An international team of researchers has taken an important step toward understanding how gene expression is controlled ...

Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee ...

GET, a novel computational model, accurately predicts gene activity by analyzing chromatin accessibility and DNA sequences ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Short-chain fatty acids (SCFAs) like propionate and butyrate are critical byproducts of dietary fiber digestion. These ...

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, according to a recent study published in ...

An AI foundation model capable of predicting gene activity across many different human cell types may expedite research for ...

Researchers hope the AI tool will aid in the development of cell-specific gene therapies to treat diseases such as cancer.

Oregon Health & Science University has a leading role in a new database designed to track the normal expression of genes in ...

Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer ...

The authors present new expression analysis software (TEKRABber) to help analyze expression correlations between transposable elements (TEs) and KRAB zinc finger (KRAB-ZNF) genes in experimentaly ...