The Kowalinski group at EMBL Grenoble discovered notable differences between the nuclear cap-binding complex in trypanosomes and humans, a critical component in cellular RNA metabolism. Trypanosomes ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

A new study from the Kowalinski group at EMBL Grenoble characterized the structure of an important trypanosomal protein ...

Earlier this week, the American Cancer Society released the full list of 245 new and renewed research grants that were ...

Key achievements in 2024: Delivered proof-of-mechanism data from a single dose of WVE-006 from the first two patients in the RestorAATion-2 clinical trial of Pi*ZZ AATD patients, representing the ...

Entering 2025 having demonstrated rapid translation of genetic insights to positive clinical data; advancing clinically validated and multi-modal ...

"By targeting key processes like RNA splicing and modification ... Leslie's powerful and robust model systems to nail down this novel mechanism," said co-corresponding author Robert Spitale ...

By targeting key processes like RNA splicing and modification ... Leslie's powerful and robust model systems to nail down this novel mechanism." The UC Irvine scientists partnered with Clotilde ...

For the multifaceted and complex diseases, multi-omics could define groups of patients with distinct endotypes exhibiting heterogeneous treatment responses due to their particular underlying molecular ...

Activating agents enable the efficient preparation of organozinc complexes from zinc metal and organohalides, but their mechanisms had been obscured by the heterogeneous nature of these systems.