Translation of human pluripotent stem cells into cell therapies ... obtain sufficient numbers of undifferentiated cells, a defined method of differentiation and validated testing methods to ...

Pluripotent stem cells are cells that have the capacity to self-renew by dividing and to develop into the three primary germ cell layers of the early embryo and therefore into all cells of the ...

Exogenous addition of retinoic acid drives differentiating human embryonic stem cells towards atrial‐like cardiomyocytes. COUP‐TFI and COUP‐TFII are induced during atrial differentiation. COUP‐TF ...

Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.

Human HSCs derived from bone marrow, peripheral blood, umbilical cord blood or pluripotent stem cells • Differentiation of HSCs toward specific hematopoietic lineages • Differentiation of MSCs toward ...

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

The emergence of induced pluripotent stem cell (iPSC) technology has had a great impact on the field ... investigate the effects of different compounds on the cellular electrophysiology of the cells, ...

However, little research has been done on their use in MS. Induced pluripotent stem cells are adult stem cells, usually from skin cells, reprogrammed to become stem cells. There isn’t much ...

This important study reveals a role for IκBα in the regulation of embryonic stem cell pluripotency. The solid data in mouse embryonic stem cells include separation of function mutations in IκBα to ...

Here we bio-printed mesenchymal stem cells (MSCs) using a commonly used bioink sodium alginate-gelatin blends, and investigated the induction effect of MSC differentiation towards lens epithelial stem ...

The Oregon Stem Cell Center conducts basic and applied research in the field of Stem Cell Biology with the long term goal to harness the properties of stem cells for regenerative medicine and cell ...

Their collaboration has resulted in engineered cells called ‘synthetic organizers’ that deliver instructions to stem cells, telling them to grow into specific tissues and organs.