Currently, there are several therapies that target cell signaling networks in PC. However, PC is a “cold tumor” with a unique immunosuppressive tumor microenvironment (poor effector T cell ...

100 and 11 significant genes were identified by support vector machine recursive feature elimination (SVM-RFE ... processed by the combat function of the sva package of the R-4.2.2 package, and ...

Each gene tells a cell to make a specific molecule, but this isn't performed by the DNA itself. Instead, the information is relayed to cellular machinery by a molecule called messenger RNA.

New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who carry disease-causing genes experience no symptoms. Every biology student ...