A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an increase in intestinal permeability allows the natural gut bacteria to cross the ...

The human immune system is like an army of specialized soldiers (immune cells) each with a unique role to play in fighting ...

In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

The three-signal model provides an empirical framework for innate instruction of adaptive immunity, but mainly discusses STAT-dependent cytokines in T cell activation and differentiation, while the ...

The study of avian and fish erythrocytes presents a unique opportunity to explore their multifaceted roles beyond oxygen transport, particularly in the ...

This discovery sheds light on how tissue-resident memory CD8 T cells adapt to their location in the body, ensuring a ...

Rakesh Jain PhD, Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk ...

A topical treatment combining calcipotriol and 5-FU shows promise in reducing premalignant lesions and lowering skin cancer ...

Adaptive immunity is the protection of a host organism from a pathogen or toxin. It is mediated by B cells and T cells, and is characterized by immunological memory. Adaptive immunity is highly ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...