uhn.ca Objective To develop new classification criteria for systemic lupus erythematosus (SLE) jointly supported by the European League Against Rheumatism (EULAR) and the American College of ...

EULAR/ACR SLE classification criteria were not linked to mortality or hospitalization, a developed ominosity model adequately predicted mortality.

Objective Metabolic reprogramming plays a critical role in modulating the innate and adaptive immune response, but its role ...

Objective Evaluating the potential role of neuromuscular ultrasonography (NMUS) in assessing optic nerve affection in ...

Jan. 21, 2025 — Researchers identified a key protein as a potential therapeutic target for stopping the body's immune system from mistakenly attacking itself, offering new hope for treating ...

Patients fulfilling the American College of Rheumatology (ACR)/EULAR 2016 criteria for pSS without other CTD diagnosis and having anti-RNP antibodies, without anti-DNA antibodies were searched in the ...

7.“A few months after getting H1N1 flu, I started sleeping for very long periods of time (up to 20 hours, sometimes two days ...

Objective In 2011, the American College of Rheumatology (ACR) and EULAR endorsed provisional criteria for remission in rheumatoid arthritis (RA), both Boolean-based and index-based. Based on recent ...

Speed limits on hundreds of UK roads will increase by 50%. Welsh routes with 20mph limits will revert to 30mph after a U-turn ...

The presence of antiarrestin autoantibodies among patients with SLE is associated with an increased risk of developing HCQ-related retinal toxicity.

However, for the vast majority of lupus flares the initial treatment has to be systemic glucocorticoids. For most manifestations, prednisone at 0.25–0.5 mg/kg body weight (or equivalent ...

Agents such as azathioprine, methotrexate and cyclosporine A have been used for several decades in the management of SLE, but the evidence for their efficacy in nonrenal lupus has remained limited.