New study reveals that TLE6 protein deficiency causes male infertility in mice. These findings suggest potential genetic ...

This new tool, known as minimal, versatile genetic perturbation technology (mvGPT), combines the powers of gene editing, ...

CRISPR-Cas systems have been exploited for targeted genome editing. Applying the CRISPR-Cas9 system to edit high GC content genomes has been challenging due to its high off-target activity.

Industrial microbiology is a branch of applied microbiology in which microorganisms are used in industrial processes; for example, in the production of high-value products such as drugs, chemicals ...

Scientists studying an aggressive cancer that affects thousands of dogs annually have uncovered a genetic signature that ...

Advances in CRISPR technologies promise to accelerate the burgeoning pipeline of gene-editing therapies and broaden access to these disease-altering therapies.

The field of cancer research is rapidly evolving, with a growing focus on the intersection of cancer immunology, gene editing, and epigenetics. This ...

Bacterial and viral infections activate the signal transduction networks that regulate the innate immune system, and trigger the production of inflammatory mediators to combat these pathogens.

To tackle a backlog in toxicity testing, US federal scientists are modernizing programs with high-throughput assays and AI.

July 22, 2024 — The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for ...

Mackie and colleagues present a valuable comparison of lateralized gustation in two well-studied nematodes. The evidence they present that ASEL/R lateralization exists and is achieved by different ...