Cellular senescence, where cells permanently stop dividing, plays a complex role in liver health. In a recent review article, ...

脂肪肝疾病发展至肝细胞癌（HCC）的机制一直是现代医学研究中的重要课题。在2025年1月1日发表在Nature期刊上的一篇题为“FBP1 controls liver cancer evolution from senescent MASH hepatocytes”的研究中，来自华西医院和美国加州大学圣地亚哥分校的联合科研团队揭示了一个关键的酶——果糖-1,6-二磷酸酶1（FBP1）在这个过程中所 ...

When a person donates a portion of their liver (living donation), the remaining liver tissue can regenerate to its original size. This regeneration occurs through the division of hepatocytes (liver ...

Liver hepatocyte organoids derived from normal (left) or mutant (right) mice showing accumulation of lipids (in green). Higher levels of lipids accumulate as big droplets inside each cell (nuclei ...

2025 年的钟声刚刚敲响，四川大学已接连在 Nature、Science、Cell 三大国际顶刊上发表文章。 2025 年 1 月 1 日，四川大学古丽、重庆大学朱亚辉及加州大学圣地亚哥分校 Michael Karin 共同通讯在 Nature ...

However, as the researchers discovered, this isn't what happens in liver cells, also known as hepatocytes. In hepatocytes, some damaged cells survive this process. These cells are, according to ...

as cell membrane stabilisers and permeability regulators that prevent hepatotoxic agents from entering hepatocytes; (iii) as promoters of ribosomal RNAsynthesis, stimulating liver regeneration ...

Ultrasound of the liver shows a fluid-filled mass with a ... biopsy the viable portion of tumor and avoid the adjacent normal hepatocytes or necrotic portions of the lesion. The two solid white ...

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