Deep within the nucleus of every cell lies a structure smaller than a pinpoint that may hold the secret to aging. Scientists ...

More than a decade of research shows that the nucleolus—the largest structure in the eukaryotic nucleus—plays a pivotal role in aging. Now, a new study analyzing yeast cells suggests both that the ...

. Published by Oxford University Press 198 Madison Avenue, New York, New York 10016, USA; 1997. pp. 360. $45.00 Whereas the yeast Saccharomyces cerevisiae has been the preferred tool for many ...

Changes in chromatin structure ... loss is coupled to cell division and seems to be triggered by telomeric DNA damage. Figure 2: Replicative ageing causes histone loss in yeast and human fibroblasts.

RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases during ... each component catalytic module of tRNA ligase is essential for yeast cell growth; ...