Other signaling molecules must move much farther ... In fact, there are hundreds of receptor types found in cells, and varying cell types have different populations of receptors.

Cell signaling is also critical for regulating tissue development and homeostasis. Time often matters for cells to make fate decisions in interpreting different types of signals. Cells not only read ...

Cell signaling is also pivotal for multi-cellular ... provide an updated synthesis of the knowledge on an intriguing type of T cell response, the public T cell response. Autophagy is a “self ...

Stanford Medicine scientists are generating a periodic table of sorts for psychiatric disorders, providing a better ...

In this advancement, we can identify new chemical entities, pharmacological agents and pharmacophores which influences the receptors mediated cell signalling in diverse cell types. In addition, new ...

Through association with the adaptor protein Myd88, interleukin receptor associated kinases (IRAK)1 and 4 initiate signaling downstream of IL-1Rs resulting in the activation of the NFkB and MAPK ...

Type I interferon signalling modulates immune responses during infection and has been implicated in autoimmunity and cancer. Type I interferon signals via the Janus kinase/signal transducer and ...

For example, Notch signalling is active at very high levels in human t-cell lymphoblastic leukemia, Necakov says, and turning off the Notch pathway in this case, and in other types of cancer, “shuts ...