The genetic information stored in DNA is a living archive of instructions that cells use to accomplish the functions ... the protein-based filaments necessary for muscle contractions. RNA ...

How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA.

This discovery led to the concept of the ribosome as a ribozyme, an RNA molecule ... of translation. rRNA plays a critical role in the assembly and maturation of ribosomes. The process of ribosome ...

Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

Users learn that molecular shape determines RNA function and allows ... processes involved as DNA builds RNA (transcription) and as RNA builds proteins (translation). The RNA Origin of Life ...

This process of protein synthesis occurs in two stages - transcription and translation. When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA).

Next, a ribosome uses the message encoded in RNA to build proteins ... in crucial cellular functions cooperate with each other. To investigate how translation and transcription work together ...

RNA is integral to cellular function ... are crucial for translation. The model also identified conserved Kozak sequence motifs — nucleic acid motifs that initiate protein translation in ...

Specifically, we investigate how 3′UTRs regulate protein functions in a manner that is independent of protein abundance. We found that inclusion or exclusion of the 3′UTR of an mRNA that encodes a ...

RNA acts as a messenger and regulator in the process of gene expression. Messenger RNA (mRNA) carries the genetic information from DNA to the ribosomes, where proteins are synthesized. Transfer RNA ...