This triggered the DNA-damage response (DDR; a signalling pathway that repairs DNA damage and limits the division of cells carrying harmful mutations), subsequent activation of TP53 and elevated ...

deriving elephant iPSCs proved challenging because these animals have a complex gene pathway not found in other species. The researchers overcame this by suppressing core genes called TP53 that ...

Two abstracts presented at the 2024 American Society of Hematology Annual Meeting & Exhibition provided insight into MDS ...