Because of this flexibility, the 30 to 40 tRNAs present in a cell can "read" all 61 codons in mRNA. The opposite end of the folded structure, which is the 3' end of the tRNA, binds to its ...

The popularity of mRNA-based therapeutics has surged over the past few years. To ensure the safety of these treatments, scientists need to analyze the characteristics of the manufactured molecules, ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

Crossing the BBB is difficult because the structure has evolved to keep out virtually any dangerous or foreign molecules, including most medicines; mRNA molecules are too large to penetrate the ...

Following the lead of previous work on mRNA-based vaccines, therapies for spinal cord injuries and more, the method relies upon mineral-coated microparticles to deliver mRNA that encodes for ...