In most recent advancements, RNA editing uses the CRISPR-Cas13 system, a newer technique that was created specifically to help develop therapies that work with RNA. DNA editing is permanent, which ...
Mammalian RNAs can be edited by the conversion of adenosine to inosine, which is read as guanosine, but technological constraints have limited our view of the overall contribution of RNA editing ...
Shares in Wave Life Sciences rose by 74% after it reported clinical data with a pioneering new RNA-editing therapy for alpha-1 antitrypsin deficiency (AATD). Wave claims this is the first clinical ...
The only industry-led meeting showcasing the recent development of RNA editing mechanisms and dedicated to realizing the research and therapeutics opportunity of RNA editing as quickly as possible.
It’s the same when trying to fix a genetic problem. Rather than fix it at source (DNA editing), you can upload a patch (RNA editing), which is less complex, more efficient and carries less risk.” ...
Inosine can also be introduced into RNA through a process called A-to-I RNA editing. In this process, adenosine deaminases acting on RNA (ADARs) convert adenosine (A) to inosine (I) by hydrolytic ...
New research has identified a critical fall-back mechanism used by the cells when the usual RNA editing process is switched off. Professor Carl Walkley heads the RNA Biology and Innate Immune ...
“We are pioneering the RNA editing field with unmatched platform capabilities and a growing pipeline of innovative GalNAc programs for cardiometabolic diseases. We have also translated our ...