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Translation of human pluripotent stem cells into cell therapies will require ... be assessed by evaluation of histone modification and DNA methylation 21,22. Defining a consistent product is ...

New research adds to our understanding of the function of the human genome. An international team of researchers has made ...

Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.

Structural Basis for Nick Recognition by a Minimal “Pluripotent” DNA ligase Although ChVLig lacks the large N- or C-terminal flanking domains found in eukaryotic cellular DNA ligases, it can sustain ...

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells ...

This important study reveals a role for IκBα in the regulation of embryonic stem cell pluripotency. The solid data in mouse embryonic stem cells include separation of function mutations in IκBα to ...

An international team of researchers has taken an important step toward understanding how gene expression is controlled ...

We apply both precision gene editing and large-scale CRISPR screening in human pluripotent stem cells (hPSCs) to explore mechanisms underlying human development ... and to understand the epigenetic ...

Ginkgo Bioworks (NYSE: DNA), which is building the leading platform for cell programming and biosecurity, today announced a ...

Ginkgo Bioworks (DNA) announced a research collaboration with Universal Cells, an Astellas (ALPMY) company, to optimize next-generation induced ...