Levandowski, CB; Jones, T; Gruca, M; Ramamoorthy, S; Dowell, RD;* Taatjes, DJ.* The ∆40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription ...
p53 has both transactivation and transrepression activity, and so controls the transcription of numerous genes. Among the p53 target genes are WAF1, an inhibitor of cyclin-dependent protein ...
Activating Transcription Factor 2 (ATF2 ... is dependent on the status of the p53 protein, a well-known tumor suppressor. In cells with wild-type p53, ATF2 enhances sensitivity to cisplatin ...
Future Oncol. 2012;8(6):683-686. Collectively, these studies suggest that elevated levels of some p53 isoforms may have favorable prognostic significance, which implies that the extent of function ...
Levandowski, CB; Jones, T; Gruca, M; Ramamoorthy, S; Dowell, RD;* Taatjes, DJ.* The ∆40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription ...
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Persistent activation of DNA damage response in the liver after MASLD reversalWD-induced MASLD triggered persistent activation of the DNA damage response (DDR) and its primary transcription factor, P53, ...
The aim of the present work was to establish an association between wood smoke exposure and lung cancer pathogenesis, and to analyze the effects of wood smoke on p53 and murine double minute 2 ...
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