In evaluating the expression of various genes related to colorectal carcinogenesis, they also observed that, in 71% of the patients who had high levels of oxidative stress, the p53 gene presented ...

In this case, the researchers engineered the tumors to express mutated versions of cancer-linked genes Kras, p53, and APC, which are often found in human colon cancers. Once these tumors were ...

Loss of p53 strongly drives the progression of disease from Barrett's to cancer. The team found that potentially cancerous cells that lost both CDKN2A and p53 were weakened and unable to compete ...

Low-dose aspirin significantly reduced risk for colorectal cancer recurrence among patients with mutations in the PI3K pathway, according to results of the randomized ALASCCA study presented at ASCO ...

A new research paper was published in Oncotarget's Volume 16 on January 21, 2025, titled "Assessment of cfDNA release dynamics during colorectal cancer surgery." ...

Expert Rev Mol Diagn. 2008;8(3):277-288. Loss of heterozygosity (LOH) can be defined as the manifestation that results from the loss of large genomic regions. Lack of amplification of a particular ...

These EVs could be isolated non-invasively from a patient’s body for early diagnosis of cancer. Colon cancer ranks 8th and rectal cancer ranks 9th among men. Annually, cases of colorectal cancer ...