The new insights on osteosarcome could, with time, lead to better treatment options and outcomes for patients through more ...

Thus, all mutations that affect the fitness of future generations are agents of evolution. Mutations are essential to evolution. Every genetic feature in every organism was, initially, the result ...

We detected small subclonal mutations ... in the evolution of CLL. The progressive accumulation of driver alterations gradually shortened the TTFT independently of the clonal architecture ...

A new study reveals a mutation mechanism in osteosarcoma, promising advances in treatment and prognosis for this challenging ...

(Mutations do create a minor amount of change ... Without the need for males, every clonal individual passes a full set of identical genes onto the next generation. In addition, a single female ...

Clonal hematopoiesis develops when a single HSC acquires growth-promoting mutations and begins to churn out many, many clones of itself. Eventually, these mutated blood cells become over ...

Clonal hematopoiesis develops when a single HSC acquires growth-promoting mutations and begins to churn out many, many clones of itself. Eventually, these mutated blood cells become over ...

A study identified the mutation mechanism LTA chromothripsis in 50% of high-grade osteosarcoma cases, explaining its genomic ...

Dr. Cecilia Yeung’s research focuses on genomic changes, clonal evolution, and epigenetic control of gene expression in myeloid neoplasms (MDS, MPN and AML) and she has developed research expertise in ...