Expansion microscopy: principles and uses in biological research Late one night in 2012, in the windowless basement of Boyden’s MIT lab, Chen and Tillberg immersed a brain slice in a bath of the ...

Cryo electron microscopy (cryo EM) has revolutionized our understanding of the intricate molecular machinery that governs life. In this article, we discuss what cryo EM is, how it works, it's ...

Scanning near-field optical microscope (SNOM) - using the scattered light through a sub-wavelenght aperture to form an image. (Illustration by Kristian Molhave, Opensource Handbook of Nanoscience and ...

The excitation is typically performed using a focused laser beam. The core principle of STED microscopy is the selective deactivation of fluorophores using stimulated emission. A second laser, called ...