Next, the team wanted to test the effects of STM2457 on the m6A process. This molecule is a specific inhibitor of METTL3 and was recently shown to be a potential anticancer therapy. In an FGR ...

This modification stabilizes SlALKBH2, enhancing its role in fruit development without affecting its m6A demethylase activity. The research also identifies NADPH-thioredoxin reductase C (SlNTRC) as a ...

RNA methylation is a chemical change that attaches a small marker molecule to RNA molecules ... which studies RNA modifications like m6A methylation, which can significantly influence gene ...

Here, the authors developed a strategy based on multichrome encoding and “AND” Boolean logic recognition, termed as PREEM, for multiplexed imaging of m6A modifications of single-cell RNA.