highlighting the structural basis of defective LDLR function. The study underscores the critical role of LDLR in LDL dimerization and cellular uptake, offering structural insights into receptor ...

Once processed by LPL, the VLDL becomes a VLDL remnant. The majority of the VLDL remnants are taken up by the liver via the LDL receptor, and the remaining remnant particles become IDL ...

In contrast, eNOS is not activated by purified forms of the major HDL apolipoproteins ApoA-I and ApoA-II or by low-density lipoprotein ... reveal that scavenger receptor-BI (SR-BI) mediates ...

Study deciphers the molecular handshake between LDL receptors and apoB100 ... Disruptions in LDLR function or apoB100 mutations, as seen in FH, lead to low-density lipoprotein cholesterol ...