An IBEC-led study describes the development of an innovative method to control the formation of crypt-like structures and ...

These Lgr5+ cells were located at the very bottom of glands, or crypts, in the intestinal lining. However, in the last decade, problems with this model began to appear. Deleting the Lgr5+ cells in ...

Intestinal stem cell-specific TLR4 expression affects the proliferation and apoptosis rate in the intestinal crypt. In addition, stem cell lineage commitment is also influenced by stem cell ...

It is accomplished by stem cells that originate in intestinal crypts—microscopic depressions in the intestinal wall. In stark ...

In a recently published Science paper, 1 his team described how they developed a biomaterial tissue scaffold that allows intestinal stem cells to self-organize into organoids with patterned crypt-like ...

An IBEC-led study describes the development of an innovative method to control the formation of crypt-like structures and ...

A contact protein printing technique enables researchers to control the formation of villi in human gut models, making it ...

Previous investigations have demonstrated that lactoferrin in human colostrum stimulates thymidine uptake into the DNA of harvested mature rat intestinal crypt cells. The effect of cow milk- and ...

We spatiotemporally pattern these cues using photoinduced degradation, viscoelasticity, and bond formation to study how intestinal stem cell colonies respond to alterations in geometric confinement, ...

A human intestinal organoid, displaying typical ‘budding crypts’ and a central ‘villus-like’ domain. The main intestinal cell types are shown in green, blue, red and purple. Membranes are ...

To understand the sequence of these early events, the researchers did a timed deletion of one or both aPKC in intestinal epithelial cells ... This was followed by the appearance of precancerous cells ...