DNA polymerase is responsible for the process of DNA replication, during which a double-stranded DNA molecule is copied into two identical DNA molecules. Scientists have taken advantage of the ...
Scientists have yet to identify a polymerase that can add bases to ... During circular DNA replication, the excised primer is readily replaced by nucleotides, leaving no gap in the newly ...
A team has unearthed new findings about what happens during the minutes and hours after a cell divides, expanding our understanding of human biology -- and potentially leading to better medicines.
Free DNA nucleotides – needed to form the new strands. DNA polymerase – an enzyme that adds new nucleotides to a growing strand of DNA. Primers – A primer is a short strand of nucleotides th ...
DNA replication is the process by which the DNA molecule makes an exact copy of itself during cell division. The double helix unwinds, and each strand serves as a template for the synthesis of a new ...
Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex (the ...
The following is a summary of “Faulty Gap Filling in Nucleotide Excision Repair Leads to Double-Strand Break Formation in ...
“It’s a different way of thinking about replication that ... Hundreds of Unintended Mutations in DNA Instead, the progress of the “lagging strand” polymerase looks a lot like stop and ...
Identifying how the polymerase is regulated to switch on and switch off the different enzymatic activities that are required ...
During DNA replication, the complementary base pairing of thymine with adenine ensures the accurate copying of genetic information. DNA polymerase enzymes use the existing DNA strand as a template and ...
the helix structure is unwound special molecules break the weak hydrogen bonds between bases, which are holding the two strands together this process occurs at several locations on a DNA molecule ...
A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication.