DNA polymerase is responsible for the process of DNA replication, during which a double-stranded DNA molecule is copied into two identical DNA molecules. Scientists have taken advantage of the ...
Free DNA nucleotides – needed to form the new strands. DNA polymerase – an enzyme that adds new nucleotides to a growing strand of DNA. Primers – A primer is a short strand of nucleotides th ...
DNA replication is the process by which the DNA molecule makes an exact copy of itself during cell division. The double helix unwinds, and each strand serves as a template for the synthesis of a new ...
the helix structure is unwound special molecules break the weak hydrogen bonds between bases, which are holding the two strands together this process occurs at several locations on a DNA molecule ...
“It’s a different way of thinking about replication that ... Hundreds of Unintended Mutations in DNA Instead, the progress of the “lagging strand” polymerase looks a lot like stop and ...
In addition, we study an ancient yet error-prone DNA repair pathway, termed micro-homology mediated end-joining, and focus on polymerase theta, a key enzyme underlying mutagenic repair. Lastly, we ...
Kossel was later awarded the Nobel Prize in Physiology or Medicine in 1910 for his contributions to the understanding of nucleic acids and proteins. During DNA replication, the double helix unwinds, ...
This is because the replication block can be overcome with the help of a specialized polymerase that can insert adenine in place of the blocking DNA residue. Using the whole genome sequencing ...
Acyclovir gets converted to acyclovir triphosphate, which then inhibits replication of herpes viral DNA by competitively inhibiting viral DNA polymerase, incorporating into and terminating the ...