The CIBER system works by using CRISPR-guide RNA (gRNA) to knock out (incapacitate) a specific gene in each cell, which in turn is barcoded into the sEVs the cell releases. This enables the ...

This repository focuses on predicting the strength of CRISPRi-mediated gene repression using machine learning. By leveraging reported features from modern literature, including gRNA sequences and ...

The investigator will provide or purchase the CRISPR gRNA(s). TGEF will inject gRNAs and cas9 into pronuclei or cytoplasm of fertilized mouse eggs and transfer them to surrogate mothers. Tail tips ...

由于CD4 + T细胞代表潜伏HIV-1库的主要部分，小组将这种CD3重靶向技术与dCas9-VPR CRISPR-VPR激活系统、最佳的HIV-1特异性gRNA-V和基于tBid的自杀基因策略相 ...

CRISPR-Cas systems are prokaryotic immune systems that confer resistance to foreign genetic elements such as plasmids and phages. CRISPR-Cas systems have been exploited for targeted genome editing ...

Can the TMM design guide RNAs to my gene of interest and generate CRISPR/Cas9 components for our lab? At this time, this is not a service offered by the TMM. OHSU users have had success designing and ...

The company provides a comprehensive range of genome editing solutions, including CRISPR proteins, mRNA, plasmids, and guide RNA (gRNA). To streamline and accelerate tool development, TMO has also ...

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.

Figure 1 Schematic diagram of CRISPR/Cas9 plant transformation vector pKSE401. Oligonucleotides of gRNA sequence were annealed and then inserted at the BsaI-digestion site between the pU6-26 promoter ...