Interactions between β-catenin and LEF-1/TCF, APC and conductin/axin are essential for wnt-controlled stabilization of β-catenin and transcriptional activation. The wnt signal transduction ...
Hwang et al., Direct Targeting of b-Catenin by a Small Molecule Stimulates Proteasomal Degradation and suppresses Oncogenic Wnt/β-Catenin Signaling. 2016, Cell Rep. 16, 28–36. Tanton et al., ...